Infections caused by non-tuberculous mycobacteria (NTM), such as Gardening Tools Mycobacterium abscessus, elicit diverse cell death mechanisms including apoptosis, necrosis, and pyroptosis, which play key roles in immunopathogenesis.NTM can manipulate these cell death pathways to evade host immune responses, ensuring their intracellular survival an
In vascular biology, endothelial KCa2.3 and KCa3.1 channels contribute to arterial blood pressure regulation by producing membrane hyperpolarization and smooth muscle relaxation.The role of KCa2.3 and KCa3.1 channels in the pulmonary circulation is not fully established.Using mice with genetically encoded deficit of KCa2.3 and KCa3.1 channels, this
Parametric statistical methods, such as Z-, t-, and F-values, are traditionally employed in functional magnetic resonance imaging (fMRI) for identifying areas in the brain that are active with a certain degree of statistical significance.These parametric methods, however, have two major drawbacks.First, it is assumed that the observed data are Gaus
The current cycle slip detection methods of Global Navigation Satellite System (GNSS) were mostly proposed on the basis of assuming the ionospheric delay varying smoothly over time.However, these methods can be invalid during active ionospheric periods, e.g., high Kp index value and scintillations, due to the significant increase of the ionospheric
The mechanical performance of underground flexible structures such as buried pipes or culverts made of plastics depend not only on the properties of the structure, but also on the material surrounding it.Flexible drains can deflect by 30% with the joints staying tight, or even invert.Large deformations of the structure are difficult to model in the